Events
Conferences
23/04 - 26/04/2024
FrenchBic annual meeting / French-Japanese Symposium on BioInorganic chemistry
We are happy to announce that the French-Japanese Symposium on BioInorganic chemistry Symposium will be held from 23 to 26 April 2024 in Marseille (France). |
Training
17/06 - 21/06/2024
Liquid and solid NMR practical training
Practical training organized at the University of Lille in order to acquire concrete notions on the use of liquid and solid NMR devices in order to be autonomous |
industrial
25/06/2024
INFRANALYTICS: Support for manufacturers and innovation
INFRANALYTICS Day: help for manufacturers and innovation |
News
Monitoring interactions between antibiotics and their targets within bacterial cells by in cell nuclear magnetic resonance (NMR) spectroscopy.
In this research work, our team explored the possibility of using nuclear magnetic resonance (NMR) in cell, that is to say directly on bacterial cell cultures, to characterize the bacterial periplasm, a front-line cellular compartment. of the action of antibiotics. The objective was to follow the fate of these antibiotics in this compartment, in the presence or absence of the expression by the bacteria of β-lactamase enzymes linked to bacterial resistance. This study shows that in cell NMR constitutes a powerful analytical tool for the study of new molecules targeting the molecular components of the bacterial periplasm.
Structural heterogeneity of a phototransformable fluorescent protein impacts its photochemical properties
Photoconvertible fluorescent proteins such as mEos4b change color when illuminated by UV light.
Infrastructure life
User portrait: Cyril Charlier
Researcher within the Nuclear Magnetic Resonance team at TBI, Toulouse
Find a platform